Immunotherapy of pancreatic cancer and the application of DNT cell in the therapy of pancreatic cancer / 国际外科学杂志
International Journal of Surgery
;
(12): 349-352, 2018.
Artigo
em Chinês
| WPRIM
| ID: wpr-693244
ABSTRACT
Pancreatic cancer is a kind of malignant tumor with a high degree of malignancy and a very poor prognosis.The onset is occult,early metastasis is easy,and progression is rapid.Despite clinically increasing the resection rate of pancreatic cancer,the survival time after surgery is not significantly prolonged.Pancreatic cancer is not sensitive to radiotherapy and chemotherapy,so there is no effective treatment.Adoptive immunotherapy is an important auxiliary method for the treatment of malignant tumors and refers to killing the malignant tumor cells in patients by injecting effective immune cells into the patient without damaging the patient's own immune system.The DNT cells discovered in recent years,namely TCR +,CD3 +,CD4-,and CD8-T cells,are T-cell subpopulations with unique immunomodulatory functions,and their expression of Fas/FasL,TNF/TNFR,and MHCI,etc.They have an important role in anti-tumor,immune regulation,immunosuppression,etc.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
International Journal of Surgery
Ano de publicação:
2018
Tipo de documento:
Artigo
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