Effect of Shuangbo San on Promoting Recovery of Gastrointestinal Function of Prostatic Cancer Patients After Laparoscopic Radical Prostatectomy / 广州中医药大学学报

ABSTRACT

Objective To investigate the effect of Shuangbo San on promoting the recovery of gastrointestinal function of prostatic cancer patients after laparoscopic radical prostatectomy(LRP). Methods Sixty-five prostatic cancer patients after LRP were randomly divided into treatment group and control group. The treatment group (N = 33)was treated with postoperative conventional western medicine combined with acupoint application of heated Shuangbo San on Shenque(CV8), and the control group(N = 32) was treated with postoperative conventional western medicine. The treatment lasted for 7 continous days. The clinical outcomes included time for the recovery of bowel sounds, postoperative exsufflation time, postoperative defecation time, time for the relief of abdominal distension and pain, average hospitalization time and total effective rate. Results (1) Time for the recovery of bowel sounds, postoperative exsufflation time, and postoperative defecation time in the treatment group were shortened as compared with the control group, the difference being significant (P < 0.05 or P <0.01). (2) After treatment, time for the relief of abdominal distension and pain, and average hospitalization time in the treatment group were shorter, and Visual Analogue Scale (VAS) scores of abdominal distension and pain were less than those in the control group, the difference being significant(P<0.01).(3) The total effective rate of the treatment group and the control group was 93.94％, 71.88％ respectively, the difference being statistically significant (P < 0.05). Conclusion Acupoint application of heated Shuangbo San on Shenque(CV8) is effective on promoting the exsufflation and defecation of post-LRP prostatic cancer patients, relieving abdominal distension and pain, promoting the recovery of gastrointestinal function, reducing the risk of postoperative intestinal obstruction and shortening hospitalization time, and has certain advantages as compared with postoperative conventional western medicine.