The immune state in patients with hepatocellular carcinoma before and after radiofrequency ablation treatment: recent progress in research / 介入放射学杂志

ABSTRACT

After radiofrequency ablation (RFA) treatment,the tumor cells of hepatocellular carcinoma (HCC) will develop coagulation necrosis and apoptosis,producing in situ tumoural antigens which may directly or indirectly stimulate the body's innate and adaptive immune responses to help reverse the body's immune suppression status.This paper aims to make a comprehensive review about the RFA-induced local and systemic immune response,innate immune,adaptive immune and their regulating roles for cytokines in HCC patients,and to further clarify the immune state changes in HCC patients after RFA treatment.