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The Clinical Effect of Administration of Magnesium Sulfate in Cardiac Surgery / 대한흉부외과학회지
The Korean Journal of Thoracic and Cardiovascular Surgery ; : 366-375, 2006.
Artigo em Coreano | WPRIM | ID: wpr-69472
ABSTRACT

BACKGROUND:

Hypomagnesemia is a common complication after cardiac surgery with cardiopulmonary bypass. The purpose of this study was to assess the clinical beneficial effect of administration of magnesium sulfate in cardiac surgery. MATERIAL AND

METHOD:

Thirty five patients scheduled for elective cardiac surgery were randomly assigned to magnesium group (n=20) which received magnesium sulfate in priming solution (1 g) and cardioplegic solution (1 g) or control group (n=15) which did not receive it. Arterial blood samples were drawn for measuring Mg++ and electrolytes contents, blood gas analysis, CBC, total protein, albumin, blood urea nitrogen (BUN), creatinine, alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin, tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), interleukin-10 (IL-10), creatine phosphokinase (CpK), creatine kinase-MB (CK-MB), lactate dehydrogenase(LDH), troponin-I (TNI), prothrombin time (PT) and activated pratial thromboplastin time level (aPTT). Venous blood samples were drawn before and after the operation for measuring activated clotting time level (ACT).

RESULT:

Mg++ levels in magensium group were higher than those of control group at intraoperative and postoperative periods (p<0.05). dysrhythmias were lower in magnesium group (8 cases out of 17 patients, 46.4%) than in control group (10 cases out of 10, 100%, p=0.050).

CONCLUSION:

These results showed that administration of low dose magnesium sulfate during cardiac surgery prevented hypomagnesemia and lowered incidence of dysrhythmia.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Período Pós-Operatório / Tempo de Protrombina / Aspartato Aminotransferases / Cirurgia Torácica / Bilirrubina / Gasometria / Nitrogênio da Ureia Sanguínea / Tromboplastina / Soluções Cardioplégicas / Ponte Cardiopulmonar Tipo de estudo: Estudo de incidência / Estudo prognóstico Limite: Humanos Idioma: Coreano Revista: The Korean Journal of Thoracic and Cardiovascular Surgery Ano de publicação: 2006 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Período Pós-Operatório / Tempo de Protrombina / Aspartato Aminotransferases / Cirurgia Torácica / Bilirrubina / Gasometria / Nitrogênio da Ureia Sanguínea / Tromboplastina / Soluções Cardioplégicas / Ponte Cardiopulmonar Tipo de estudo: Estudo de incidência / Estudo prognóstico Limite: Humanos Idioma: Coreano Revista: The Korean Journal of Thoracic and Cardiovascular Surgery Ano de publicação: 2006 Tipo de documento: Artigo