Research advances of endoplasmic reticulum stress in high glucose environment and its related ophthalmic diseases / 国际眼科杂志(Guoji Yanke Zazhi)
International Eye Science
;
(12): 1038-1042, 2018.
Artigo
em Chinês
| WPRIM
| ID: wpr-695368
ABSTRACT
· Endoplasmic reticulum (ER) is a place where it folds and synthesizes the proteins.ER stress was induced when a variety of physiological and pathological factors happened,under which the protein misfolding occurred,the unfolded protein accumulated and the calcium ion imbalanced in the ER.The ER of high-glucose environment can change the protein redox state and produce reactive oxygen species,which affects the ER channel function and chaperone protein buffer;meanwhile changes the balance of calcium ions;finally induces the formation of ER stress.More and more studies have confirmed that ER stress in high glucose environment can cause a variety of ophthalmic diseases.So we review the recent articles about ER stress of high glucose environment and its related ophthalmic diseases.
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Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
International Eye Science
Ano de publicação:
2018
Tipo de documento:
Artigo
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