Analysis of factors for lateral neck lymph node metastasis in cN0 papillary thyroid carcinoma / 中华内分泌外科杂志
Chinese Journal of Endocrine Surgery
;
(6): 509-512, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-695489
ABSTRACT
Objective To explore the lateral neck lymph node metastasis (LNM) in patients affected by papillary thyroid carcinoma(PTC) with clinically negative neck (cN0-PTC) and to discuss the necessity of prophylactic lateral neck lymph node dissection.Methods Clinical data of 651 cN0-PTC patients who underwnt surgical procedure in Tumor Hospital of Zhengzhou University from Jan.2012 to May.2015 were retrospectively analyzed.Chi-square test was used for univariate analysis.Results Of the 651 cN0-PTC patients,62.9% had LNM (51.3% in central neck,41.0% in lateral neck,and 11.7% with "skip" metastasis).The lateral neck metastasis rate was 50.9% in men and 37.7% in women (P<0.05),61.9% in patients with tumor diameter >1.0 cm and 25.9% in patients with tumor diameter ≤ 1.0 cm (P<0.001),47.2% with multifocal cancer and 40.3% with unifocal tumor(P<0.05),63.1% with extrathyroidal extention and 34.3% without extention (P<0.001),64.1% with ≥3 positive nodes in central neck and 48.3% with <3 positive nodes (P<0.05),52.4% with upper lobe cancer and 32.9% with other locations(P<0.001),41.0% in patients ≤45 years and 40.9% in patients >45 years(P>0.05).Conclusion Central neck dissection should be performed in all cN0-PTC patients.Prophylactic lateral neck dissection should beselectively performed in cN0-PTC patients with following high-risk factorsmale,tumor diameter >1.0 cm,multifocal cancer,extrathyroidal extention,≥ 3 positive nodes in central neck and upper lobe cancer.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Fatores de risco
Idioma:
Chinês
Revista:
Chinese Journal of Endocrine Surgery
Ano de publicação:
2017
Tipo de documento:
Artigo
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