Related factors for complicating depression in patients with polycystic ovarian syndrome / 中华内分泌外科杂志

ABSTRACT

Objective To explore risk factors of depression in patients with polycystic ovarian syndrome (PCOS).Methods 142 patients diagnosed as PCOS and meeting criterions were collected from Aug.2013 to Nov.2016 in our hospital.Demographic data,menstrual status,signs,serum hormone levels,treatment were collected and recorded.The degree of depression was evaluated by Hamilton Depression scale (HAMD).They were divided into two groupsdepression and non-depression group.Univariate x2 test and multivariate logistic regression analysis were used to explore risk factors for complicating depression in patients with PCOS.Results Depression occurred in 44 patients (30.98％),with 28 cases of mild depression,14 cases of moderate depression,and 2 cases of severe depression.Univariate x2 test revealed that BMI (x2=4.385,P=0.036),infertility (x2=8.367,P=0.004),LH/FSH (x2=4.592,P=0.032) and serum levels of FT (x2=5.777,P=0.016) were factors related to depression.Multivariate logistic regression analysis revealed that BMI＞25 kg/m2 (OR=12.874,95％ CI1.675～75.824,P=0.013),infertility (OR=17.526,95％ CI1.436～94.335,P=0.008),LH/FSH＞2 (OR=7.326,95％ CI1.263～43.128,P=0.021) and abnormal FT (OR=9.724,95％ CI3.625～56.524,P=0.016) were risk factors of depression.Conclusions Patients with PCOS have mild or moderate depressive tendencies.BMI＞25 kg/m2,infertility,LH/FSH＞2,abnormal FT were the risk factors of depression.