The effects of serum potassium on insulin secretion ability in patients with impaired glucose regulation / 中华内分泌外科杂志
Chinese Journal of Endocrine Surgery
;
(6): 330-334, 2018.
Artigo
em Chinês
| WPRIM
| ID: wpr-695576
ABSTRACT
Objective To explore whether serum potassium can influence insulin secretion ability in pa tients with impaired glucose regulation (IGR).Methods 320 subjects with IGR were enrolled in our study.All subjects underwent a standard OGTT.Their clinical and biochemical parameters were measured.Insulin secretion indices were measured by DI0,DI30,and DI120.Results In IGR,DI0 was negatively correlated with BMI (r=-0.122,P=0.015),total cholesterol (TC) (r=-0.182,P=0.032),low density lipoprotein-cholesterol (LDL-C) (r=-0.1 78,P=0.026) and triglyceride (TG) (r=-0.179,P=0.01 1).DI30 was negatively correlated with TC (r=-0.146,P=0.001),TG(r=-0.192,P=0.027)and LDL-C(r=-0.134,P=0.014).DI120 was negatively correlated with TC(r=-0.222,P< 0.001),TG(r=-0.209,P<0.001)and LDL-C (r=-0.183,P<0.001) while postively correlated with serum potassium (r=0.208,P<0.001).The multiple regression model analysis showed that serum potassium (β=0.380,P<0.001) was independently correlated to DI120.Conclusion In patients with IGR,serum potassium is associated with insulin secretion ability,which may provide a new treatment strategy for preventing IGR into T2DM.
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DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Endocrine Surgery
Ano de publicação:
2018
Tipo de documento:
Artigo
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