Metabolic memory and diabetic nephropathy / 复旦学报（医学版）

ABSTRACT

Metabolic memory is a phenomenon that the diabetic complications continue to develop and progress in individuals who exposed a period of high glucose in the early stage and then returned to normal blood glucose after effective control.Diabetic nephropathy (DN) is one of the common diabetic microangiopathy and the main cause of end stage renal disease (ESRD).This review mainly summarizes the relationships between metabolic memory and the development of DN.