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Evaluation of LD BC-Ⅰ Blood Cell Image Automatic Analyzer in Analysis of the Nucleated Cells in Peripheral Blood Smear / 现代检验医学杂志
Journal of Modern Laboratory Medicine ; (4): 86-90, 2018.
Artigo em Chinês | WPRIM | ID: wpr-696215
ABSTRACT
Objective To verify and evaluate the clinical performance of LD BC-Ⅰ blood cell image automatic analyzer.Methods A total of 202 EDTA-Na2 anticoagulant blood specimens were collected at the hospital clinic randomly between October and December 2016.After wright staining,each specimen was examined by microscopy and automatic analyzer respectively,the detection efficiency and the results of nuclear cells classification were compared between artificial microscopy and automatic analyzer,the correlation and consistency of two methods were further analyzed.Results The average time required for each specimen of the automatic analyzer was reduced by 3.81 minutes when compared with artificial microscopy,the P values was less than 0.01.LD BC-Ⅰ agreed 71.4%,64.8%,28.8%,21.1% and 71.6% respectively for pre-differentiation of the blast cells,promyelocytes,myelocyte,metamyelocytes and atypical lymphocytes.The diagnosis accordance rates of five nucleated cells above increased to 87.7%,81.5%,38.1%,26.3% and 86.2% after manual review.Passing Bablok regression analysis found that the correlation coefficient (r) of two methods of neutrophils was 0.981,lympho kjcytes (r =0.894),monocytes (r=0.725),eosinophils (r=0.772),and there were significant correlation between two methods (all P <0.01).Bland-Altman analysis found that the coincidence rate of the neutrophils and lymphocytes were 96%,the monocytes were 91% and the eosinophils were 94%.Conclusion The LD BC-Ⅰ automatic blood cell image analyzer could significantly improve the analysis efficiency of the nucleated cells.There was good consistency in the classification results of mature granulocytes,monocytes and lymphocytes between instrumental detection and artificial microscopy.The method has certain clinical value to be applied widely.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Guia de Prática Clínica Idioma: Chinês Revista: Journal of Modern Laboratory Medicine Ano de publicação: 2018 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Guia de Prática Clínica Idioma: Chinês Revista: Journal of Modern Laboratory Medicine Ano de publicação: 2018 Tipo de documento: Artigo