X-linked agammaglobulinemia in children / 中华实用儿科临床杂志
Chinese Journal of Applied Clinical Pediatrics
;
(24): 288-291, 2018.
Artigo
em Chinês
| WPRIM
| ID: wpr-696380
ABSTRACT
X-linked agammaglobulinemia (XLA) is one of the most common types of primary immunodeficiency disease in children,and is an antibody deficiency disease which is seen in men.Most XLA patients carry mutations in Bruton tyrosine kinase (BTK) gene,they typically present with very low numbers of peripheral B cells and a profound deficiency of all immunoglobulin isotypes.XLA is characterized by recurrent bacterial infections within 2 years,sometimes life-threatening.The prognosis of XLA has been improved by the treatment of gammaglobulin that allow normal concentrations of serum IgG.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Applied Clinical Pediatrics
Ano de publicação:
2018
Tipo de documento:
Artigo
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