Current situation and treatment of fat - soluble vitamins deficiency in infants with biliary atresia / 中华实用儿科临床杂志

ABSTRACT

Biliary atresia (BA)is a serious disease with early onset and persistent obstructive jaundice as the main symptom. The reducing of bile acid,decreasing of liver function and the ability of protein production,cause the fat - soluble vitamins deficiency is common in BA patients. The fat - soluble vitamins A,D,E and K deficiency will cause night blindness,adverse calcification of bone,neurological disorders,blood coagulation dysfunction and other sys-tems dysfunction. The treatment is mainly supplement of fat - soluble vitamins including internal and external supple-mentation,different dosage forms,and individualized supplement and detection. Although fat - soluble vitamins deficien-cy in children with BA has been reported,the severity,correlation with liver function,and treatment results have not been paid much attention.