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Bartter syndrome and Liddle syndrome / 中华实用儿科临床杂志
Chinese Journal of Applied Clinical Pediatrics ; (24): 1289-1292, 2018.
Artigo em Chinês | WPRIM | ID: wpr-696580
ABSTRACT
Bartter syndrome and Liddie syndrome are genetic renal tubular disorders characterized by hypokalemic alkalosis.Bartter syndrome is mainly an autosomal recessive disease,caused by mutations of one of the five ion channel genes in renal tubular epithelial cells.Plasma renin and aldosterone levels are increased but blood pressure is normal,the main treatment is to correct hypokalemia,to prevent and cure complications.Liddle syndrome is an autosomal dominant disease,caused by epithelial Na-channel gene mutation,and presented with increased blood pressure but decreased plasma levels of renin and aldosterone.Patients with Liddle syndrome should limit the intake of sodium and supplement potassium,take Triamterene or Amiloride to control hypertension.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Applied Clinical Pediatrics Ano de publicação: 2018 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Applied Clinical Pediatrics Ano de publicação: 2018 Tipo de documento: Artigo