The epidemiology of thoracic aorta and coronary calcification in lung cancer screening using low dose chest CT / 实用放射学杂志

ABSTRACT

Objective To investigate the epidemiological characteristics of thoracic aorta and coronary calcification,and to analyze the effects of common risk factors on thoracic aorta and coronary calcification.Methods Low dose chest CT was performed in 2 393 asymptomatic subjects who underwent lung cancer screening.The chi-square test and Logistic regression analysis were used.Results The frequency of aortic calcification was 24.73％ in total 2 393 subjects.And the frequency of calcification was the highest in the arch.The frequency of aortic calcification was 8.82％,and the frequency of calcification was higher in the left coronary artery than the right coronary artery.The frequency of thoracic aorta and coronary calcification were increasing with age,and the frequency of calcification was higher in male than female (P ＜0.05).The frequency of calcification was higher in smokers than non-smokers,and the frequency of calcification was higher in smokers (≥30 capsules) than the smokers (＜30 capsules) (P＜0.05).The age,smoking and chronic bronchitis were associated with thoracic aorta and coronary calcification.Conclusion The detection of calcification of thoracic aorta and coronary in lung cancer screening using low dose chest CT can assess the epidemiological characteristics of atherosclerosis in healthy screening population.