Explore CT classification and clinical significance for minimal lung adenocarcinoma / 实用放射学杂志

ABSTRACT

Objective To focus on CT classification and clinical significance for minimal lung adenocarcinoma(MIA),to improve the knowledge of this kind of lung adenocarcinoma.Methods 51 cases of MIA confirmed by histopathology were retrospectively evaluated in our hospital,which were analyzed and classified by CT manifestation.Results Of the 51 patients,according to CT features ,lesions were divided into three typespure ground-glass nodule (pGGN)(34 cases),mixed ground-glass nodule(mGGN)(8 cases),Part-solid GGN (9 cases).The maximum diameter of pGGN ranged from 0.62-2.41 cm (1.01 cm±0.36 cm),the overall density was uniform and the CT value-plus ranged from 150-512 HU (266 HU±81 HU).mGGN showed scattered punctate or rounded,oval shaped high density in GGN in lung window,which was not visible in mediastinal window.Part-solid GGN showed solid component in both lung window and mediastinal window and the longest average diameter of the solid component ranged from 0.02-0.49 cm(0.2 cm±0.16 cm).While no statistical differences were found between the three types in shape,margin,air bronchogram,pleural retraction,vessel dilatation, but lobular,burr and pleural retraction were observed more frequently in Part-solid GGN and mGGN than that in pGGN.In addition, 50% of lobulation were deep lobulation,which was showed statistical difference between pGGN and mGGN/Part-solid GGN groups. Conclusion MIA has multiple CT manifestations,the morphology and size of solid component plays an important role in the diagnosis of MIA. For pGGN,lesion size and CT value-plus should be considered when diagnosing MIA.