The factor analysis of chemotherapy related symptoms among patients with gastrointestinal cancer / 中国实用护理杂志

ABSTRACT

Objective To investigate the status and influencing factors of symptom clusters in patients with gastrointestinal cancer receiving FOLFOX6 chemotherapy. Methods Totally 100 patients with gastrointestinal cancer receiving FOLFOX6 chemotherapy were investigated using MD. Anderson Symptom Inventory-Chinese (MDASI-C) and Social Support Rating Scale (SSRS). Results The top incidences and severity of symptoms was lack of appetite.Exploratory factor analysis showed three main symptom clusters: gastrointestinal symptom clusters, physical symptom clusters and mental symptom clusters. The number of courses of chemotherapy was the influencing factor of gastrointestinal symptom clusters, physical symptom clusters. For mental symptom clusters, social support was the influencing factor. Conclusions Patients with gastrointestinal cancer suffer from multiple symptoms during FOLFOX6 chemotherapy. The results are good for establishing early predictions of symptoms and providing scientific evidence for the interventions of symptoms clusters.