The relation with the location of infarction and brain natriuretic peptide, left ventricular ejection fraction for first acute ST-segment elevation myocardial infarction / 实用医学杂志

ABSTRACT

Objective This study investigated the relation with the location of infarction and brain natriuretic peptide (BNP),left ventricular ejection fraction (LVEF) for first acute ST-segment elevation myocardial infarction.Methods From January 2014 to December 2016,163 consecutive patients with ASTEMI who admitted to our hospital were enrolled in this study,were divided by infarction position.All the patients were classified into wide anterior infarction group,anterior infarction group,anterior septal infarction group and inferior infarction group.The BNP level and the LVEF were measured for 163 consecutive patients respectively on admission and after six-month follow-up visit and record the adverse cardiovascular events,comparing their relations.Results The BNP level of wide anterior infarction group were all significantly higher than all the other groups on admission and after six-month follow-up visit,but the LVEF were significantly lower than all the other groups (P ＜ 0.05).The BNP level of anterior infarction group were significantly higher than anterior septal infarction group and inferior infarction group on admission and after six-month follow-up visit,but the LVEF were significantly lower than anterior septal infarction group and inferior infarction group (P ＜ 0.05).The BNP level of anterior septal infarction group were higher than inferior infarction group on admission and after six-month follow-up visit,but the LVEF were lower than inferior infarction group (P ＜ 0.05).Meanwhile,the incidence of adverse cardiovascular events of the wide anterior infarction group,anterior infarction group,anterior septal infarction group were all larger than inferior infarction group,and the wide anterior infarction group was the largest.Conclusion There is a close relationship with infarction position,BNP and LVEF.The location of infarction,BNP level and LVEF counld all be recognized as the important predicted indicator of adverse cardiovascular events,premature complication and prognosis.