Research progress on the relationship between microRNA-196a and tumor / 实用肿瘤学杂志

ABSTRACT

As a member of the miRNA family,microRNA-196a(miR-196a) has received much attention in recent years. MiR-196a not only plays an important regulatory role in various biological processes, but it also shows that miR-196a also func-tions as oncogene in the tumorigenesis and progression. In recent studies, miR-196a is high expression in the serum, tissues and cells of patients with cancer,and can promote tumor cell proliferation,invasion and metastasis,inhibit tumor cell apoptosis and en-hance tumor drug resistance. In this paper,we reviewed the research progress on the correlation between miR-196a and tumor based on the latest reports at domestics and abroad.