Roles of Treg Cells and Th17 Cells in Treatment of Inflammatory Bowel Disease / 胃肠病学

ABSTRACT

Inflammatory bowel disease(IBD)is a kind of non-specific intestinal inflammatory disease. The immune imbalance of intestinal mucosa is the main cause of IBD. Regulatory T cells(Treg cells)are important immune-regulatory cells,and helper T cells 17(Th17 cells)participate in host immune defense. The balance between Treg cells and Th17 cells is an important factor to maintain intestinal immune homeostasis. This article reviewed the roles of Treg cells and Th17 cells in the treatment of IBD.