Autoimmune Liver Diseases and Liver Transplantation / 胃肠病学

ABSTRACT

Liver transplantation is a well accepted treatment for patients with end-stage liver disease. The indications of liver transplantation for autoimmune liver diseases such as autoimmune hepatitis,primary biliary cholangitis,and primary sclerosing cholangitis are similar to that with other acute or chronic liver diseases. Despite liver transplantation has a favorable overall outcome in these patients,the recurrence of autoimmune liver diseases is relatively common and challenges remain in terms of the management and survival of graft. It should be noted that de novo autoimmune hepatitis can arise in patients transplanted for non-autoimmune liver diseases. In this article,the indications and outcomes of liver transplantation in patients with autoimmune liver diseases were discussed for the better understanding of liver transplantation in this setting.