Intervention and mechanism of exercises on primary osteoporosis / 中国组织工程研究

ABSTRACT

BACKGROUND: With the acceleration of aging population in the world, the prevalence of primary osteoporosis is increasing. Complications induced by primary osteoporosis will be a key public health problem, so its prevention and treatment is an issue of concern in the medical field. OBJECTIVE: To clarify the benign intervention mechanism of exercises on primary osteoporosis, and to analyze the mechanism of exercise effects on primary osteoporosis by literature and logical thinking methods, so as to find out the benign intervention mechanism, thereby providing theoretical reference for the patients and surgeons.METHODS: A computer-based online search was conducted in Elsevier Science-direct, Medline, EM, CNKI, and CJFD databases using the key words of "sports, osteoporosis, nutrition, hormone, depression" in English and Chinese, respectively. The search years ranged from 1990 to 2015. Totally 756 relevant articles were screened, and 52 eligible articles were finally included for analysis and discussion. RESULTS AND CONCLUSION: Primary osteoporosis is affected by hormone, nutrition, exercise, lifestyle and psychological factors. Exercises can mediate the secretion of hormones to regulate bone mass, which is a kind of direct physical stimulation to bone metabolism, further affecting the absorption of nutrients to maintain bone mass. Exercise makes active effect on lifestyle and psychology, thus affecting bone health. Therefore, the scientific and reasonable exercise has a benign intervention action on primary osteoporosis, and can be used to prevent primary osteoporosis.