Clinical Observation of Cannulated Compression Screw Tunnel Recombined Human Bone Morphogenetic Protein - 2 Implantation for Treatment of Femoral Neck Fracture / 现代医院

ABSTRACT

Objective To observe the effect of rhBMP-2 (bone Guide) in the treatment of femoral neck fracture. Methods In our hospital from January 2016 to May 2017, 86 patients with femoral neck fracture were randomly divided into observation group and control group, 43 cases in each group. The observation group was treated with closed reduction and cannulated screw fixation compared with cannulated screw tunnel rhBMP-2 (recombinant human bone morphogenetic protein-2) implantation for the treatment of the control group. Observe the curative effect and adverse reaction. Results The observation group's bone healing rate and hip joint function score higher than the control group, and intraoperative blood loss and postoperative bed time, bed time, fracture healing time, time, the incidence of femoral head necrosis, incidence of complications were lower than those in control group. The difference was significant (P＜0.05); there was no significant difference between the two group operation time (P＞0.05). Conclusion The treatment of femoral neck fracture with bone guide and percutaneous screw placement has good therapeutic effect, and it can prompt patients to recover as early as possible and reduce the occurrence of osteonecrosis of the femoral head.