Current situation and principles of off-label drug uses / 中国小儿急救医学

ABSTRACT

Drug instructions are medical documents with legal effect. Off-label drug use exists widely worldwide,especially in cancer patients,children,pregnant women and the elderly,including unlabeled indica-tions,populations,usage and dosage. However,the government should formulate relevant laws and regulations to carry out scientific and standardized administration. To ensure the rights and interests of both doctors and patients,off-label uses should follow the corresponding principles in clinical practice.