Predictive value of lipoprotein (a) and SUA level for short-term progress of vascular lesion outside stent after PCI / 心血管康复医学杂志

ABSTRACT

Objective:To study predictive value of serum uric acid (SUA) and lipoprotein a [Lp (a)] for short-term (6-12 months) progress of vascular lesion outside stent after percutaneous coronary intervention (PCI).Methods:A total of 117 patients who received coronary angiography (CAG) twice in our hospital from Jan 2014 to Jan 2017 were selected .According to the second CAG results ,patients were divided into no progress control group (n＝62) and lesion progress group (n＝55).Index levels before the second CAG and changes between two CAG were meas- ured and compared between two groups .Multi-factor Logistic regression analysis was used to analyze independent risk factors for short-term progress of vascular lesion outside stent after PCI .Results: Compared with no progress control group ,there were significant rise in ascending ranges of Lp (a) [11.35 (-78.55 ,68.48) mmol/L vs. 65.30 (8.35 ,190.48) mmol/L] and SUA [6.50 (-16.50 ,43.00) mmol/L vs.69.50 (-14.75 ,119.00) mmol/L] between two CAG in lesion progress group ,P＝0.004 ,0.037. Multi-factor Logistic regression analysis indicated that ascending ranges of Lp (a) (OR＝1.032 ,P＝0.034) and SUA (OR＝1.007 ,P＝0.042) were independent risk factors for short-term progress of vascular lesion outside stent after PCI .Conclusion:Ascending ranges of SUA and Lp (a) are independent risk factors for short-term progress of vascular lesion outside stent after PCI .Their changes can predict risk of short-term progress of vascular lesion outside stent after PCI .