Correlation among ambulatory blood pressure indexes and P wave dispersion in patients with hyperten-sion / 心血管康复医学杂志

ABSTRACT

Objective:To explore P wave dispersion (Pd) change in patients with hypertension ,and study correlation among ambulatory blood pressure indexes and Pd .Methods: A total of 100 patients with hypertension treated in our hospital from Jul 2015 to Jul 2017 were selected as hypertension group .Another 76 healthy subjects without cardio-vascular diseases undergoing physical examination during the same period were selected as normal control group .Ac-cording to circadian rhythm of blood pressure ,hypertension group was further divided into dipper group (n＝36 ) and non-dipper group (n＝64).All subjects received 24h ambulatory blood pressure monitoring and 12-lead ECG .P wave maximum time limit (Pmax) ,P wave minimum time limit (Pmin) and Pd were compared among all groups ,and correlation among ambulatory blood pressure indexes and Pd were analyzed .Results: Compared with normal con-trol group ,there were significant rise in Pmax [ (103.13 ± 9.19) ms vs.(118.04 ± 11.14) ms] and Pd [ (24.62 ± 5.96) ms vs.(38.05 ± 7.76) ms] in hypertension group , P＝0.001 both .Compared with dipper group ,there were significant rise in Pmax[ (116.04 ± 10.17) ms vs.(121.13 ± 12.06) ms] and Pd [ (35.05 ± 8.01) ms vs.(40.05 ± 7.16) ms] in non-dipper group , P＝ 0.035 ,0.002. Pearson correlation analysis indicated that Pd was significant positively correlated with 24h mean systolic blood pressure (SBP) ,24h SBP standard deviation (SD) ,24h diastolic blood pressure SD ,SBP load ,daytime mean SBP and nighttime mean SBP (r＝0.291～0.455 ,P＜0.05 or ＜0.01). Conclusion: SBP ,SBP load and blood pressure SD are significant positively correlated with Pd in patients with hy-pertension ,suggesting that these indexes possess higher value in assessing atrial injury in these patients .