Effects of continuous theta burst stimulation (cTBS) on the motor network in motor area / 医疗卫生装备

ABSTRACT

Objective To investigate the effects of continuous theta burst stimulation (cTBS) on the motor network in the motor area,in order to provide a new way for the basic treatment of motor function.Methods A total of 12 healthy subjects were recruited to stimulate the primary motor areas of the brain by continuous theta burst transcranialmagnetic stimulation,and finger movements were tested before and after stimulation,while the EEG was collected.Pearson correlation method was used to analyze the related characteristics of EEG signals,construct and analyze the functional network of brain,and study the characteristic parameters of brain function network.Results The correlation coefficient matrix,the topological map of the functional network and the parameters of the functional network of the brain were not changed before and after the intervention in the pseudo stimulus group (all P＞0.05);Before stimulation,as compared with after stimulation,cTBS stimulated the motor area,the key button exercise test mean reaction time increased,the degree of network node decreased,the cluster coefficient increased,the network of "small world" property reduced.After cTBS stimulation,there were significant differences (P＜0.05).Conclusion The cTBS mode of transcranial magnetic stimulation (TMS) can change the topological structure and network parameters of brain function network,and improve the motor function.