Application of CRISPR/Cas9 genome editing technique in cancer / 医学研究生学报

ABSTRACT

CIustered regulatory interspaced short palindromic repeat (CRISPR)/CRISPR associated nuclease 9 (Cas9) genome editing system is the third generation genome editing system,which has been widely applied in cancer research and cancer therapeutic exploration because of high efficiency and accuracy.However,the translation from experiment to the clinic will be challenging.This review briefly introduces the mechanism of CRISPR/Cas9 and explores the potential use in studying and treating cancer disease.