Clinical value of contrast-enhanced ultrasonic contrast in the diagnosis of thyroid microcarcinoma / 中国基层医药

ABSTRACT

Objective To investigate the clinical value of contrast-enhanced ultrasonic contrast in the diagnosis of thyroid microcarcinoma .Methods A total of 115 patients with thyroid nodules diagnosed surgically and pathologically were selected .Chose a series of contrast pulse contrast imaging ( CPS ) features of Acuson sequoia 512 color Doppler ultrasound diagnostic apparatus and Italy Bracco company production of ultrasound contrast agent SonoVue, the patients received routine ultrasonography firstly , then received ultrasonic contrast.Results Of 115 nodules,49 malignant nodules,including 49 cases of papillary thyroid carcinoma ,1 case of papillary carcinoma with metastasis;66 benign nodules,including 54 cases of nodular goiter(3 cases with calcification),7 cases of adeno-mas(1 case with calcification ),left thyroid sub acute thyroiditis in 1 case,4 cases with benign nodules .Benign nodules were more common than malignant nodules , the boundary was clearly more than the malignant nodules , low echo in less malignant nodules ,the blood flow signal was less than that of malignant nodules (χ2 =9.356,9.144, 9.832,6.581,all P <0.05).Benign nodules enhanced significantly more than the uniform malignant nodules, malignant nodules enhanced significantly less than the low , enhanced significantly more than the malignant clear boundary nodules(χ2 =6.130,5.791,23.206,all P<0.05).The specificity,sensitivity and accuracy of contrast-enhanced ultrasound were higher than conventional ultrasound (χ2 =6.971, 7.462, 7.152, all P<0.05 ). Conclusion Ultrasonic contrast has high clinical value in the diagnosis of thyroid microcarcinoma , and the sensitivity , specificity and accuracy are high , and can significantly improve the detection rate of thyroid microcarcinoma .