Application of thrombus aspiration technique in emergency percutaneous coronary intervention for patients with ST segment elevation myocardial infarction / 中国基层医药

ABSTRACT

Objective To evaluate the effect of thrombus aspiration technique in emergency percutaneous coronary intervention for patients with ST segment elevation myocardial infarction ( STEMI ) .Methods According to the digital table ,48 patients with acute anterior myocardial infarction were randomly into 22 cases of control group ( routine stent implantation ) and 26 cases of observation group ( thrombus aspiration and then stent implantation ) .The changes of TIMI grading , left ventricular ejection fraction , NT -ProBNP were compared between the two groups . Results There were no significant differences in baseline data between the two groups (all P>0.05).The proportion of TIMI grade III of immediate blood flow in the observation group after operation was higher than that in the control group(26 cases vs.16 cases,χ2 =4.810,P<0.05).The LVEF values of the observation group and the control group at 1 week after operation were better than those after 24 h,but there was no statistically significant difference between the two groups (t=1.803,1.796,all P>0.05).The level of NT-ProBNP at 1 week after operation in the observation group was significantly lower than that in the control group [(271.2 ±35.5)pg/mL vs.(806.5 ±65.8)pg/mL,t=3.154,P<0.05].Conclusion The thrombus aspiration technique can obviously reduce the occurrence of the "no reflow"in STEMI patients with high thrombus load receive PPCI ,improve the heart function .