Effect of Guilongkechuanning combined with cefotaxime in the treatment of elderly patients with acute exacerbation of chronic bronchitis / 中国基层医药

ABSTRACT

Objective To investigate the clinical effect of Guilongkechuanning combined with cefotaxime in the treatment of elderly patients with acute exacerbation of chronic bronchitis .Methods 68 patients with acute exacerbation of chronic bronchitis were selected from April 2016 to March 2017 in the Third People's Hospital of Xiangshan County,and they were randomly divided into control group and observation groupaccording to the digital table,with 34 cases in each group .The two groups were given symptomatic treatment , the control group received cefotaxime treatment, while the observation group was given cefotaxime combined with Guilongkechuanning .The clinical effect , symptoms improve time , hospitalization time and lung function were observed in the two groups .Results The total effective rate of the observation group was 94.12％,which was significantly higher than 76.47％of the control group (χ2 =4.22,P<0.05).The recovery time of sputum,cough,wheezing and,hospitalization time in the observation group were (3.09 ±0.76)d,(4.28 ±0.83)d,(4.30 ±0.92)d,(7.02 ±0.66)d,respectively,which were significantly shorter than those in the control group [(5.93 ±0.60) d,(8.34 ±0.56) d,(9.19 ±1.05) d, (10.54 ±1.03)d](t=17.10,23.64,20.42,16.78,all P<0.05).After treatment,the forced vital capacity,forced expiratory volume in one second and forced vital capacity ratio in the observation group were (3937.48 ±18.99)mL, (64.28 ±3.45)％,respectively,which were better than those in the control group [(3038.42 ±20.31) mL, (57.88 ±2.89)％](t=188.54,8.29,all P<0.05).Conclusion Guilongkechuanning combined with cefotaxime in the treatment of elderly patients with acute exacerbation of chronic bronchitis has definite effect , which can effectively control the disease .