Application of ultrasound targeted microbubble destruction in gene therapy of diabetes mellitus / 中国介入影像与治疗学

ABSTRACT

Diabetes mellitus is a metabolic disease characterized by hyperglycemia,resulting in chronic damage and dysfunction of many organs,such as the eyes,kidneys,heart,blood vessels,nerves,etc.,which increase the difficulty of treatment for diabetes.In recent years,gene therapy for diabetes mellitus has become a hot topic.Ultrasound targeted microbubble destruction (UTMD) has the advantage of safety,good repeatability and tissue targeting,and has become a potential strategy for gene delivery.The related study progresses of UTMD in gene therapy of diabetes mellitus were reviewed in this article.