Transabdominal embryofetoscopy in 6 cases of first trimester prenatal diagnosis for congenital anomalies / 대한산부인과학회잡지
Korean Journal of Obstetrics and Gynecology
;
: 2351-2358, 2004.
Artigo
em Coreano
| WPRIM
| ID: wpr-70300
ABSTRACT
OBJECTIVE:
To demonstrate the efficacy of first trimester embryofetoscopy for prenatal diagnosis of congenital anomalies in continuing pregnancies.METHODS:
Under ultrasound guidance, six patients at 12+6-14+6 weeks of gestation underwent endoscopic procedures. Indications included history of 2 recurrent major genetic syndromes, history of cleft lip/palate in 2 cases, each one of the patient itself and the previous fetus and each family history of syndactyly and polydactyly. A 1 mm semirigid fiberoptic endoscope with a 18 gauge examination sheath and a single-chip digital camera were used for transabdominal embryofetoscopy.RESULTS:
Excellent visualization of the external fetal anatomy was obtained in 83% of cases (5/6) with the duration of procedures ranging 15 to 40 minutes. A diagnosis of Meckel-Gruber syndrome was made at 13+1 weeks of gestation by visualizing postaxial polydactyly and an occipital encephalocele. Subsequently the pregnancy was terminated. Three full-term infants were delivered with no gross limb or facial abnormalities. Amniotic fluid leakage after the procedure occurred in 2 cases resulting in termination of pregnancy.CONCLUSION:
Our experiences confirm the efficacy of embryofetoscopy for early diagnosis in the first trimester of pregnancy. Procedure-related risks are to be established by multicenter studies.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Primeiro Trimestre da Gravidez
/
Diagnóstico Pré-Natal
/
Ultrassonografia
/
Polidactilia
/
Sindactilia
/
Endoscópios
/
Diagnóstico Precoce
/
Diagnóstico
/
Encefalocele
/
Extremidades
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo diagnóstico
/
Guia de Prática Clínica
/
Estudo de rastreamento
Limite:
Feminino
/
Humanos
/
Lactente
/
Gravidez
Idioma:
Coreano
Revista:
Korean Journal of Obstetrics and Gynecology
Ano de publicação:
2004
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS