Research progress on establishment of animal models of ovarian cancer / 中国实验动物学报
Acta Laboratorium Animalis Scientia Sinica
;
(6): 259-264, 2018.
Artigo
em Chinês
| WPRIM
| ID: wpr-703221
ABSTRACT
Ovarian cancer is the fifth leading cause of cancer-related death in women. 75% of ovarian cancer patients were detected at an advanced stage. At present,the disease lacks effective early screening method and the clinical therapy effect is poor,which has become a serious threat to women's health. The use of animal models of ovarian cancer is an important mean to elucidate the pathogenesis of the disease,and to screen effective diagnosis and treatment. The disease models are mainly divided into four types spontaneous, induced, transplanted and gene intervention type. Mice, rats, hens,Mirotus Fortis and Mongolian gerbil are mainly selected to prepare animal models of ovarian cancer. Based on recent literature reports,we reviewed the preparation method of animal models of ovarian cancer and introduced the evaluation standards and main characteristics of these animal models.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Guia de Prática Clínica
/
Estudo prognóstico
Idioma:
Chinês
Revista:
Acta Laboratorium Animalis Scientia Sinica
Ano de publicação:
2018
Tipo de documento:
Artigo
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