A case-control study of personality disorder among senior high school students in Beijing / 中国心理卫生杂志

ABSTRACT

Objectives: To explore genetic and environmental risk factors of personality disorder (PD). Methods:By means of case-control study, 10003 senior high school students and their parents were investigated twice in first and third grades using Personality Disorder Questionnaire-fourth edition (PDQ-4), Parental Rearing Questionnaire (Egma Minnen av Bardndosnauppfor-stran, EMBU), General Information Questionnaire, and InternationalPersonality Disorder Examination (IPDE) to diagnose PD according to the criteria of ICD-10 and DSM-IV. The univariate and multivariate analysis methods were applied for data processing. Results: In the students of first grade, the risk factors of personality dysfunction were poor parental relationship, rural residential area, parental rejection, overprotection, favoring subject, non-emotional warmth, shorter time of living with parents, and male. Similar results were yielded instudents of third grades. The risk factors of PD were poor parental relationship, parental rejection, and over-protection. The heritability of overall PD of father and mother were 0. 84 and 0. 85, respectively. The heritability of each PD cluster was higher than 0. 6. Conclusion: The genetic factor plays an important role in the development of PD. Family environmental risk factors include poor parental relationship, parental rejection and over-protection.