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The role of microRNA-137 gene in schizophrenia / 中华行为医学与脑科学杂志
Chinese Journal of Behavioral Medicine and Brain Science ; (12): 85-88, 2018.
Artigo em Chinês | WPRIM | ID: wpr-704043
ABSTRACT
Schizophrenia is a chronic devastating psychiatric disorder,which severely damages pub-lic mental health. The pathophysiological mechanism of schizophrenia is complex and the etiology of schizo-phrenia is still unclear. Epidemiological study,twins study and family study show that genetic factors play a substantial part in the process of schizophrenia. Previous research indicates that there is a close association between microRNA-137 and schizophrenia,and that the ablation of microRNA-137 significantly affects clini-cal symptoms and prognosis of patients with schizophrenia. So it highlights the relationship between microR-NA-137 and schizophrenia,which reveals its special role in the etiological mechanism of schizophrenia,and may provides new perspective about the treatment of patients in schizophrenia.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo prognóstico Idioma: Chinês Revista: Chinese Journal of Behavioral Medicine and Brain Science Ano de publicação: 2018 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo prognóstico Idioma: Chinês Revista: Chinese Journal of Behavioral Medicine and Brain Science Ano de publicação: 2018 Tipo de documento: Artigo