The role of microRNA-137 gene in schizophrenia / 中华行为医学与脑科学杂志
Chinese Journal of Behavioral Medicine and Brain Science
;
(12): 85-88, 2018.
Artigo
em Chinês
| WPRIM
| ID: wpr-704043
ABSTRACT
Schizophrenia is a chronic devastating psychiatric disorder,which severely damages pub-lic mental health. The pathophysiological mechanism of schizophrenia is complex and the etiology of schizo-phrenia is still unclear. Epidemiological study,twins study and family study show that genetic factors play a substantial part in the process of schizophrenia. Previous research indicates that there is a close association between microRNA-137 and schizophrenia,and that the ablation of microRNA-137 significantly affects clini-cal symptoms and prognosis of patients with schizophrenia. So it highlights the relationship between microR-NA-137 and schizophrenia,which reveals its special role in the etiological mechanism of schizophrenia,and may provides new perspective about the treatment of patients in schizophrenia.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
Idioma:
Chinês
Revista:
Chinese Journal of Behavioral Medicine and Brain Science
Ano de publicação:
2018
Tipo de documento:
Artigo
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