Age-specific Reference Ranges for Prostate-specific Antigen in Dalian / 中国医科大学学报
Journal of China Medical University
; (12): 927-930, 2017.
Article
em Zh
| WPRIM
| ID: wpr-704920
Biblioteca responsável:
WPRO
ABSTRACT
Objective To determine the age-specific normal ranges of serum prostate-specific antigen (PSA) levels in Dalian,China.Methods Serum samples were collected from 8 453 asymptomatic men who underwent health examinations at the Second Affiliated Hospital of Dalian Medical University.Results The median PSA level was 0.93 μg/L,and the interquartile level was 0.81 μg/L.The 95th percentile level was 3.49 μg/L.The 95th percentile levels according to age group were:20 to <30 years,0 to 1.67 μg/L;30 to <40 years,0 to 2.01 μg/L;40 to <50 years,0 to 2.41 μg/L;50 to <60 years,0 to 3.25 μg/L;60 to <70 years,0 to 3.92 μg/L;70 to <80 years,0 to 5.48 μg/L;and older than 80 years,0 to 9.35 μg/L.The differences between the different age groups were statistically significant (P < 0.01).The serum PSA value was positively correlated with age (r =0.251,P < 0.001).Conclusion There were clear differences in age-specific PSA levels in Dalian,and these were lower than the standard OESTERLING.Screening for prostate cancer according to age-specific PSA reference values may be useful in the early detection of prostate cancer and may also reduce the risk of over-diagnosis.
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Índice:
WPRIM
Tipo de estudo:
Screening_studies
Idioma:
Zh
Revista:
Journal of China Medical University
Ano de publicação:
2017
Tipo de documento:
Article