Reflection and Outlook on the Current Analytical Methods for Aminoglycosides / 中国药师

ABSTRACT

The determination methods for the related substances and contents of aminoglycosides were reviewed. The HPLC-ELSD, HPLC-PAD and the other methods for the determination of aminoglycosides in Chinese Pharmacopoeia, USP and European Pharmacopoeia were introduced. The utilization specialties of the post column derivatization in detecting aminoglycosides were also in-troduced. Finally, the above three methods were compared, and the development of analytical methods for aminoglycosides was out-looked.