The effect of preoperative anxiety on propofol EC50 for no-movement during painless gastroscopy / 中国医师杂志
Journal of Chinese Physician
;
(12): 493-495, 2018.
Artigo
em Chinês
| WPRIM
| ID: wpr-705852
ABSTRACT
Objective To investigate the effect of preoperative anxiety on propofol EC50 for nomovement during Painless gastroscopy.Methods Thirty-one patients (without anxiety) and twenty-seven patients (with anxiety) undergoing gastroscopy under general anesthesia were enrolled on the study.Anesthesia was conducted with a target-controlled infusion (TCI) of propofol.The initial target effect-site propo fol concentration (Ceprop) was 5.0 μg/ml and was adjusted stepwise by 0.5 μg/ml by an up-down sequential method to reach no-movement.Results Propofol EC50 to induce no-movement was higher in patients with anxiety than those without anxiety (5.32 μg/ml,95% CI4.75-5.88 μg/ml vs 4.75 μg/ml,95% CI4.48-5.01 μg/ml,P < 0.05).Conclusions During painless gastroscopy,patients with anxiety had a higher propofol EC50 for no-movement compared with those without anxiety when intravenous injected of fentanyl 0.1 μg/kg.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Chinese Physician
Ano de publicação:
2018
Tipo de documento:
Artigo
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