Retrospective analysis of 39 cases with infective endocarditis / 中国医师杂志

ABSTRACT

Objective The clinical features,bacteriological changes,the characteristics of auxiliary examination and the timing of treatment in patients with infective endocarditis (IE) were discussed in the study retrospectively.The characteristics of the patients with infective endocarditis in our hospital in the last 8 years were summarized in order to improve the level of diagnosis and treatment.Methods From Jan.2010 to Dec.2017,39 cases of IE were admitted from the department of infectious medicine,cardiology and heart surgery in our hospital.The basic causes,clinical symptoms,signs,auxiliary examination and treatment outcome were summarized through retrospective case analysis.The results were recorded by Excel 2010 and analysed by SPSS 20.0 software.Results The total mortality rate was 7.69％ (3/39),all of which were ill treated in internal medicine.After surgery,there was no death in patients,the positive rate of blood culture was 41.03 ％ (16/39),and the rate of valvular neoplasm was 82.05 ％ (32/39) by echocardiography.Conclusions At present,the main cause of infective endocarditis is congenital heart disease,and the endocarditis caused by rheumatic heart disease is becoming less.Early diagnosis and rational selection of antibiotics and the time of operation are very critical.The significance of clinical echocardiography is greater than that of blood culture.Since the positive rate of blood culture is not satisfactory,and the strain of the bacteria has changed slightly compared with the previous reports in most foreign countries.And there is a mutual influence between the primary disease and the renal function,so it is necessary to monitor the renal function.