Application of targeted panel sequencing in prenatal diagnosis of congenital heart disease / 中国医师杂志

ABSTRACT

Fetal congenital heart disease is one of the important reasons that seriously affect the outcome of perinatal children.In recent years,with the development of molecular genetic technology,prenatal diagnosis of fetal congenital heart disease has made breakthrough progress.Targeted panel sequencing of congenital heart disease fetus can significantly improve the detection rate of chromosome copy number variations.It is helpful to correctly assess the prognosis of the fetus in prenatal clinical consultation and provide a more objective basis for pregnant women to continue their pregnancy.