Speckle tracking imaging in evaluation of left ventricular myocardial systolic rotationin patients with multiple myeloma / 中国医学影像技术

ABSTRACT

Objective To evaluate myocardial systolic rotation with speckle tracking imaging in multiple myeloma (MM) patients with normal left ventricular ejection fraction (LVEF).Methods A total of 42 patients with MM (LVEF≥50％) and 30 healthy controls (control group) were included,and the general and 2D echocardiographic parameters were analyzed.MM patients were divided into normal ventricular wall group (n=14) and thickened ventricular wall group (n=28).Results At mitral valve level,the subendocardial myocardium rotation and the whole myocardium rotation in normal ventricular wall group and thickened ventricular wall group reduced compared with those in control group (all P＜0.05).At apical level,the subendocardial myocardium rotation and the whole myocardium rotation in thickened ventricular wall group reduced compared with those in control group (both P＜0.05),and the differences of the subendocardial myocardium rotation and the whole myocardium rotation were not statistically significant between normal ventricular wall group and control group (both P＞0.05).LV torsion in normal ventricular wall group and thickened ventricular wall group reduced compared with control group (both P ＜ 0.05).The differences of subepicardial myocardium rotation were not significant neither in mitral valve level nor in apical level among three groups (P＞ 0.05).Conclusion LV rotation in patients with MM has been impaired before the appearance of characteristic echocardiographic changes,especially in subendocardial myocardium.