Combination of ultrasound guided fine needle aspiration biopsy and molecular analy-sis for the differential diagnosis of thyroid nodules / 中国肿瘤临床
Chinese Journal of Clinical Oncology
;
(24): 33-36, 2018.
Artigo
em Chinês
| WPRIM
| ID: wpr-706751
ABSTRACT
Recently,the incidence of papillary thyroid carcinoma(PTC)has been increasing yearly.Ultrasonography is considered the first tool in the screening and diagnosis of thyroid nodules.Ultrasound-guided fine needle aspiration(US-FNA)biopsy is an effective, minimally invasive intervention for the differential diagnosis of thyroid nodules before operation.The diagnosis of US-FNA is classified by the Bethesda diagnostic system. Although fine needle aspiration cytology has high sensitivity and specificity, unclear diagnoses, such as atypical follicular lesions,are still existed.US-FNA combined with genetic mutation analysis(BRAF,RAS,and RET/PTC rearrange-ment)for such atypical lesions(BethesdaⅢ-Ⅴ),as well as microRNA analysis,can significantly improve the diagnostic accuracy of in-definite nodules.This process facilitates standardized clinical management of benign and malignant thyroid nodules.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo diagnóstico
Idioma:
Chinês
Revista:
Chinese Journal of Clinical Oncology
Ano de publicação:
2018
Tipo de documento:
Artigo
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