The progress of pathogenesis and treatment in angioimmunoblastic T-cell lymphoma / 中国肿瘤临床
Chinese Journal of Clinical Oncology
;
(24): 633-637, 2018.
Artigo
em Chinês
| WPRIM
| ID: wpr-706863
ABSTRACT
Angioimmunoblastic T-cell lymphoma (AITL) is one of the most common subtypes of peripheral T-cell lymphomas. It is a fol-licular T-helper-derived neoplasm, and characterized by the presence of some genetic alterations, such as mutations in TET2, DN-MT3A, IDH2, and RHOA. Anthracycline-containing regimens represent the most widely adopted first-line option; however, new biolog-ic agents should be designed and incorporated to improve treatment response. The elucidation of the specific roles of these genetic al-terations in AITL will facilitate the development of molecularly targeted therapies to treat this disease.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo de etiologia
Idioma:
Chinês
Revista:
Chinese Journal of Clinical Oncology
Ano de publicação:
2018
Tipo de documento:
Artigo
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