Application of combined AD8 and MMSE in detecting cognitive impairment in servicemen undergoing physical examination / 中华老年心脑血管病杂志

ABSTRACT

Objective To study the sensitivity and specificity of combined AD8 and MMSE in detecting cognitive impairment in servicemen undergoing physical examination.Methods Cognitive impairment in 1723 servicemen undergoing physical examination in our hospital was assesed according to their AD8 and MMSE scores.Results The AD8 score was ≥2 in 326 (18.9％) out of the 1723 servicemen who underwent AD8 examination and in 84 (52.2％) out of the 161 servicemen who complained of cognitive impairment detected by MMSE.The MMSE was abnormal in 78 (48.4％) out of the 161 servicemen who complained of cognitive impairment.Of the 66 servicemen (41.0％) who were diagnosed with dementia,46 (69.7％) were diagnosed according to their AD8 score and 55 (83.3％) were diagnosed according to their MMSE score.ROC curve analysis showed that the specificity (91.6％) of combined AD8 and MMSE was significantly higher than that (60.0％) of simple AD8.Covariance analysis revealed that the score of trail making test-A was significantly higher while that of MMSE,delay recall,executive function,working memory and word fluency was significantly lower in servicemen with abnormal AD8 and MMSE than in those with normal AD8 and MMSE (P＜0.01).Conclusion Combined AD8 and MMSE can improve its specificity and reliability in detecting dementia in servicemen undergoing physical examination and can thus be popularized in grass-root medical and healthcare institutions.