3-year morbidity of diabetes of the middle-aged and elderly residents in a community of Guiyang and an analysis of risk factors / 中华内分泌代谢杂志

ABSTRACT

Objective To investigate the accumulative 3-year morbidity of diabetes in the residents aged 40 years and above in a community of Guiyang and the risk factors. Methods A total of 10140 permanent residents aged over 40 years in a community of Guiyang were selected from May 2011 to October 2011 using randomized sampling. This population was followed up again in 2014. Questionnaires, physical examination, blood lipids and oral glucose tolerance test were performed among the subjects of study for two surveys with the same criteria. Finally, 5958 subjects with complete data and without baseline diabetes at the two time points were enrolled in this study for analysis. Results The 3-year accumulative morbidity of diabetes in this population was 6. 13％ (6. 59％ in males, 5. 65％ in females). The main factors influencing the incidence of diabetes mellitus were age (OR = 1. 589, 95％ CI 1. 395-1. 809, P<0. 01), body mass index ( OR = 2. 012, 95％ CI 1. 632-2. 479, P<0. 01), pulse rate ( OR =1. 019, 95％ CI 1. 012-1. 025, P<0. 01), family history (OR = 1. 700, 95％ CI 1. 299-2. 225, P<0. 05), fasting plasma glucose at baseline(OR = 3. 132, 95％ CI 2. 478-3. 958, P<0. 01), 2 h plasma glucose at baseline( OR =1. 698,95％ CI 1. 574-1. 832, P < 0. 01), total cholesterol ( OR = 1. 350, 95％ CI 1. 060-1. 719, P < 0. 05), triglyceride(OR=2. 196, 95％ CI 1. 758-2. 743, P<0. 01),high density lipoprotein-cholesterol(OR = 0. 540, 95％CI 0. 375-0. 776, P < 0. 01), and low density lipoprotein-cholesterol ( OR = 1. 614, 95％ CI 1. 094-2. 382, P<0. 05). Conclusion 3-year morbidity of diabetes in Guiyang was 6. 13％ . The incidence of diabetes is notably correlated with aging, faster pulse frequency, overweight and obesity, higher baseline blood glucose, and dyslipidemia.