Relationship between Chinese visceral adipose index and obstructive sleep apnea hypopnea syndrome in patients with type 2 diabetes mellitus / 中华内分泌代谢杂志

ABSTRACT

Sleep apnea hypopnea index(AHI) was evaluated in 304 patients with T2DM using a portable sleep apnea monitor. Patients were divided into 4 groups as T2DM without obstructive sleep apnea hypopnea syndrome (OSAHS) group,T2DM with mild,moderate and severe OSAHS groups according to AHI. Patients were divided into 4 groups according to CVAI. The results suggested that the prevalence of OSAHS was 61.8% among hospitalized T2DM patients. There were significant differences in body mass index,waist circumference,Chinese visceral adipose index(CVAI),high density lipoprotein cholesterol,triglyceride and alanine aminotransferase among groups(all P<0.05). There were significant positive correlations between CVAI and AHI,GGT,ALT,AST,HOMA-IR(all P<0.01). CVAI was a risk factor of AHI according to multivariable regression analysis. CVAI may reflect the severity of OSAHS in patients with T2DM and visceral adipose deposition is a risk factor of AHI.