Risk factors of esophageal stenosis after endoscopic submucosal dissection with 1/2?3/4 circumferential mucosal defect / 中华消化内镜杂志

ABSTRACT

Objective To analyze the incidence and risk factors of postoperative esophageal stenosis after endoscopic submucosal dissection(ESD)with mucosal defect of 1/2?<3/4 circumference. Methods A retrospective analysis was performed on the data of 301 patients with early esophageal cancer or precancerous lesions undergoing ESD at Drum Tower Hospital between January 2013 and August 2015. The incidence and risk factors for postoperative stenosis were analyzed. Results Esophageal stenosis was observed in 13 cases among the 113 cases of 1/2?<3/4 circumference mucosal defect. The rate of stenosis was 11.5%. There was no significant difference between stenosis group and non?stenosis group in regard of gender, age, family history, concomitant diseases, lesion type, operation time, invasion depth, lesion longitudinal length,pathological diagnosis or complications after ESD(P>0.05),while the rate of lesions in the upper esophagus in stenosis group was higher than that in the control group(P<0.05). Conclusion Mucosal defect of 1/2?<3/4 circumference has a lower esophageal stenosis rate after ESD,which is related to the location of lesion. The ratio of upper esophagus lesion in the stenosis group is significantly higher than that in the non?stenosis group.