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The long-term impact of postoperative pulmonary complication after resection of non-small cell lung cancer / 中华胸心血管外科杂志
Chinese Journal of Thoracic and Cardiovascular Surgery ; (12): 1-5, 2018.
Artigo em Chinês | WPRIM | ID: wpr-711708
ABSTRACT
Objective To determine the long-term impacts of major pulmonary complications ( MPCs) and identify the in-dependent risk factors in those non-small cell lung cancer(NSCLC)patients who underwent VATS lobectomy.Methods A ret-rospective study was developed to analyze the pulmonary complications of 574 non-small cell lung cancer patients who under-went VATS lobectomy in Peking University Hospital , the complications were graded according to TMM classification criteria . The effects of PCs on the long-term prognosis were analyzed by using the Kaplan-Meier method.Multivariate logistic regression analysis was used to determine the risk factors of MPCs.Results Of 574 patients, 106 had PCs, including 50(8.7%) MPCs, Postoperative pulmonary complications were associated with significantly longer drainage time (P<0.001) and hospital stays(P<0.001).Perioperative mortality was significantly increased in patients with PCs (4.0% vs 0.6%; P =0.021). Those who develop a MPC had a reduced 3-year DFS and 5-year DFS(61.3% vs.77.4%、42.2% vs.69.3%;P=0.003), as well as the reduced 3-year OS and 5-year OS(78.5%vs.88.2%、62.4% vs.79.2%;P=0.047).MPCs were independ-ent prognostic factors of patients with lung cancer .Multivariate logistic regression analysis showed that the independent risk fac-tors for MPCs were age, male, ASA grade.Conclusion Major pulmonary complications after VATS lobectomy are associated with a poorer long-time outcome.The independent risk factors for MPCs are age, male, and ASA grade.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo prognóstico / Fatores de risco Idioma: Chinês Revista: Chinese Journal of Thoracic and Cardiovascular Surgery Ano de publicação: 2018 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo prognóstico / Fatores de risco Idioma: Chinês Revista: Chinese Journal of Thoracic and Cardiovascular Surgery Ano de publicação: 2018 Tipo de documento: Artigo