Assessment on right ventricular longitudinal strain and strain rate in prediabetes with two-dimensional speckle tracking imaging / 中华医学超声杂志（电子版）

ABSTRACT

Objective To predict the presence of impairment of right ventricular function in prediabetes using two-dimensional speckle tracking imaging. Methods From June 2012 to May 2016, a total of 110 patients from Zhejiang Taizhou Hospital of Taizhou Enze Medical Center (group) were recruited, including 40 controls, 33 prediabetes and 37 type 2 diabetes. The routine right ventricular parameters were measured. Longitudinal peak strain of right ventricular free wall (RVLPSF), ventricular septal (RVLPSS) and global longitudinal peak strain of right ventricle (RVLPSG) were measured with two-dimensional spekle tracking imaging, and global systolic strain rate (SRS), global early diastolic strain rate (SRE) and global late diastolic strain rate (SRL) of right ventricle were also measured. LVEDVI, LVESVI, LVEF, RVD, E/A, e/a, E/e, TAPSE, RVFAC, RVLPSF, RVLPSS, RVLPSG, SRS, SRE, and SRL in the above 3 groups were analyzed with LSD-t test. Results Compared with the controls RVLPSF, RVLPSS, RVLPSG, SRS, and SRE were all statistically reduced in prediabetes[(-27.89±4.11)% vs(-21.78±3.62)%,(-20.08±4.11)% vs (-16.88±2.68)%, (-23.98±2.96)% vs (-19.33±2.13)%, -1.67±0.25 vs -1.18±0.24, and 1.84±0.23 vs 1.35±0.20,t=3.45,3.42,3.44,3.44,and 3.43,all P<0.01].RVLPSF,RVLPSS,RVLPSG,SRS,and SRE were all statistically reduced in diabetes[(-27.89±4.11)% vs(-20.97±3.88)%,(-20.08±4.11)% vs(-15.42±1.92)%, (-23.98±2.96)% vs(-18.19±2.29)%,-1.67±0.25 vs-1.08±0.23,and 1.84±0.23 vs 1.18±0.27,t=3.43,3.45,3.43, 3.42,and 3.42,all P<0.01].Compared the prediabetesSRE was significantly reduced in diabetes(1.35±0.20 vs 1.18±0.27, t=3.45, P<0.01). Conclusions Diastolic and systolic function of right ventricle were already impaired in prediabetes, and speckle tracking imaging can quantitatively evaluate the impairment.