Coronary Flow Reserve in Non-Infarcted Myocardium Predicts Long-Term Clinical Outcomes in Patients Undergoing Percutaneous Coronary Intervention
Yonsei Medical Journal
;
: 252-257, 2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-713096
ABSTRACT
PURPOSE:
Coronary flow reserve (CFR) is recognized as an indicator of myocardial perfusion. The aim of this study was to assess the relationship between CFR in the non-infarcted myocardium and the incidence of major adverse cardiac events (MACEs). MATERIALS ANDMETHODS:
100 consecutive patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI) were enrolled in the present study, and divided into MACE and non-MACE groups according to the incidence of 12-month MACEs. Left ventricular function and CFR were analyzed using two-dimensional echocardiography and myocardial contrast echocardiography at one week after PCI. Cardiac troponin I levels were assayed to estimate peak concentrations thereof.RESULTS:
The MACE group was associated with lower CFR, compared to the non-MACE group (2.41 vs. 2.77, p < 0.001). In the multivariable model, CFR in the non-infarcted myocardium was an independent predictor of 12-month MACE (hazard ratio 0.093, 95% confidence interval 0.020–0.426, p=0.002) after adjustment for baseline demographic and clinical characteristics.CONCLUSION:
CFR in the non-infarcted myocardium is a useful marker for predicting 12-month MACEs in patients with AMI undergoing primary PCI.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ecocardiografia
/
Modelos de Riscos Proporcionais
/
Função Ventricular Esquerda
/
Resultado do Tratamento
/
Circulação Coronária
/
Reserva Fracionada de Fluxo Miocárdico
/
Imagem de Perfusão do Miocárdio
/
Intervenção Coronária Percutânea
/
Infarto do Miocárdio
/
Miocárdio
Tipo de estudo:
Estudo prognóstico
Limite:
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Yonsei Medical Journal
Ano de publicação:
2018
Tipo de documento:
Artigo
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